Advancing open science and developing research-ready resources that accelerate autism research are central components of the Simons Foundation Autism Research Initiative (SFARI)’s mission. SFARI has generated a wealth of genomic and phenotypic data across several autism and related neurodevelopmental disorder cohorts and has also supported, through external grants, the generation of additional large datasets. In parallel, many other data resources have emerged. While such datasets have already been used to ask important questions relevant to autism, many opportunities for additional analyses and modeling remain, should scientists have the time and resources to invest in these directions. We are aware that further analyses of existing datasets are often not incentivized to the same degree as collection of new data.

The goal of this award is to increase use of large, publicly available data resources by supporting investigators to allocate time and personnel toward working in and publishing from these previously collected data. Applications should leverage existing publicly accessible datasets to ask new questions and extract new knowledge. Priority will be given to applications that use SFARI-supported resources, although all applications will be considered as long as data are publicly accessible at the time of application. Proposed questions should be relevant to SFARI’s mission.